Wernicke-Korsakoff encephalopathy and the endorphin system.
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چکیده
منابع مشابه
Wernicke-Korsakoff encephalopathy and the endorphin system.
Sir, We read with interest the recent paper of Gibb et al. (1985) in which reversible coma in Wernicke's encephalopathy was reported. Treatment with thiamine was successful in that the patient regained consciousness but unsuccessful in preventing the residual amnestic defect of Korsakoff's encephalopathy. In a similar report (Wallis et al., 1978) four comatose patients with the Wernicke syndrom...
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Carl Wernicke described first Wernicke encephalopathy in 1881. He reported a pathological clinical situation, which comprises a triad of symptoms with acute mental confusion, ataxia, and ophthalmoplegia. He described three patients, two with a story of high alcohol consumption and one patient with persistent vomiting that presented with progressive stupor and coma, progressing to death. After t...
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Wernicke-Korsakoff syndrome is a manifestation of thiamine (vitamin B1) deficiency, usually secondary to alcohol abuse, although there other non-alcohol related causes, such as bariatric surgery, and extreme dietary restriction. The syndrome is a combined manifestation of the short-lived but acute Wernicke’s encephalopathy (WE), followed by chronic Korsakoff syndrome. It is generally accepted t...
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AIM Presented is the neuroradiological signature of acute Wernicke's encephalopathy (WE), derived from different types of magnetic resonance imaging (MRI) sequences. WE results from thiamine depletion, and its most typical antecedent is chronic alcohol dependence. Brain regions observed with in vivo MRI affected in acute WE include the mammillary bodies, periaqueductal and periventricular gray ...
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Seventeen severe chronic alcoholic patients with and without Wernicke-Korsakoff syndrome (WKS) were examined prospectively after being treated by withdrawal from alcohol. The WKS patients also received thiamine supplements. Three-dimensional measurements of local cerebral blood flow (LCBF) and local partition coefficients (L lambda) were made utilizing xenon contrast computed tomography (Xe CT-...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1986
ISSN: 0032-5473
DOI: 10.1136/pgmj.62.726.315